The Campus of Patras is situated in the suburb of Rion which is 8 km North East of the City of Patras within the Municipality of Patras. Rion has become a very important transportation junction for Western Greece especially since the development of the bridge Rion-Antirrion which connects Patras' easternmost suburb of Rio to the town of Antirrio, connecting the Peloponnese Peninsula with Mainland Greece giving residents and visitors quick and easy access by car to Mainland Greece and Epirus (Sterea Ellada & Epirus) as well a frequent ferry boat service. Nowadays, the suburb of Rio has developed into a lively destination with plenty of schools, commercial shops, restaurants, amusements centres and hotels. The University Regional General Hospital of Patras is located next to the University of Patras.

The seafront of Rio with its pebbled beaches, clear blue waters and restaurants is one of the most beautiful tourist attractions within the prefecture of Achaia. There are many choices of entertainment for the residents of Rio and Patras. One of the highlights of Rio is a large fortress with bastions and a courtyard that is surrounded by a sunken stone fence and is built on the sea border of Rio and which stands out like an ornament adorning it especially during sunset. The Fortress has a small church within which caters for weddings and in the courtyard cultural activities, live shows, theatrical performances etc are hosted.

Rio is subdivided into the villages of Agios Vassileios with its restaurants, which has a beautiful view to the Patraikos Gulf, Arachovitika where there is a curative spring, Drepano for visitors who enjoy windsurfing, the picturesque village of Psathopirgos, in all these little villages you can enjoy the sea and view of the mainland while eating fresh fish in one of the many fish taverns. For residents and visitors who enjoy the mountains, the little village of Sella, where you can enjoy the gastronomic traditional dishes, in Kastritsi you can enjoy the wonderful view, the cherry trees and the springs and in Platani village where there is one of the oldest churches in the region of Achaia named Agios Nikolaos which was built in the 11th century.

Thus, the University of Patras is situated in one of the most picturesque towns of the Municipality of Patras, where one has easy access to both sea and mountain.